VEGF ANTAGONIST FORMULATIONS SUITABLE FOR INTRAVITREAL ADMINISTRATION

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专利权人:

REGENERON PHARMACEUTICALS; INC.

发明人:

Eric FURFINE,Daniel DIX,Kenneth GRAHAM,Kelly FRYE

申请号：

US16739559

公开号：

US20200131246A1

申请日:

2020.01.10

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Ophthalmic formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided suitable for intravitreal administration to the eye. The ophthalmic formulations include a stable liquid formulation and a lyophilizable formulation. Preferably, the protein antagonist has an amino acid sequence of SEQ ID NO:4.

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