DOSAGE POUR LA SENSIBILITÉ DU CANAL HERG À DES AGENTS PHARMACOLOGIQUES À PETITES MOLÉCULES

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专利权人:

The Rockefeller University

发明人:

MACKINNON, Roderick,SU, Zhenwei,WANG, Weiwei

申请号：

EP17776767

公开号：

EP3435955A4

申请日:

2017.03.31

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

The present invention provides methods and compositions relating to an assay for hERG channel protein sensitivity to small molecule pharmacological agents. In one embodiment, the invention includes an engineered hERG channel protein. In another embodiment, the invention includes a method of identifying small molecule pharmacological agents that interfere with repolarization of cardiac cells.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/