BARRETT, Stephen Douglas,CISKE, Fred Lawrence,COLOMBO, Joseph Michael,ENDRES, Gregory William,GERMAIN, Bradlee David,KOMILOV, Andriy,KRAMER, James Bernard,UZIEBLO, Adam,MAXEY, Kirk M.
申请号：
AU2017200044
公开号：
AU2017200044A1
申请日:
2017.01.04
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
#$%^&*AU2017200044A120170202.pdf#####DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASE AND CONDITIONS ABSTRACT Disclosed herein are compounds of formula (I) and therapeutic methods of treatment with compounds of formula (I), where Li, L2, L4, R4, R5, R6 and s are as defined in the specification. Compounds of formula (I) are EP4 agonists useful in the treatment of glaucoma, neuropathic pain, and related disorders. 1 0 F O N F L L SRG OH
