A synthetic construct suitable for implantation into a biological organism that includes at least one polymer scaffold wherein the at least one polymer scaffold includes at least one layer of polymer fibers that have been deposited by electrospinning wherein the orientation of the fibers in the at least one polymer scaffold relative to one another is generally parallel, random, or both and wherein the at least one polymer scaffold has been adapted to function as at least one of a substantially two-dimensional implantable structure and a substantially three-dimensional implantable tubular structure.