The invention provides methods and apparatus for reconstituting fluids and substances and injecting the reconstituted materials. Apparatus may include an injection needle having a hub, a draw-up needle having a hub, and a safety cap for engagement with a syringe barrel or reservoir for transfer and/or reconstitution and injection of fluids. The apparatus includes engagement means for securely engaging the hubs of the needles and/or cap to minimise inadvertent pricks with either of the needles during the filling of a syringe with reconstituted materials and injecting the materials. Preferably the engagement means incorporates a channel on one hub and a protrusion on the other hub. The system may incorporate a second bore for quick draw-up of materials and fluids for injection. Preferably, the apparatus comprises of polymeric materials which can be injection moulded. The invention includes methods for drawing-up and reconstituting fluids for injection.
