The present invention relates to an orally disintegrating tablet of a multilayer structure, which has (1) a layer that contains enteric coated microgranules containing a proton pump inhibitor, and (2) a layer that contains acetylsalicylic acid. The orally disintegrating tablet is characterized in that: the active ingredients thereof (the proton pump inhibitor and aspirin) have high stability; and pharmacological effects of the active ingredients are exhibited stably and quickly after administration.