GROENEWEGEN, RUDOLF JOHANNES JOSEPH,DE GRAAFF, WOUTER,OUT, HENK JAN
申请号:
PL04741599
公开号:
PL1631255T3
申请日:
2004.05.19
申请国别(地区):
PL
年份:
2013
代理人:
摘要:
The subject invention provides a drug delivery system comprising at least one compartment consisting of (i) a drug-loaded thermoplastic polymer core, (ii) a drug-loaded thermoplastic polymer intermediate layer and (iii) a non-medicated thermoplastic polymer skin covering the intermediate layer, wherein said intermediate layer is loaded with (a) crystals of a first pharmaceutically active compound and with (b) a second pharmaceutically active compound in dissolved form and wherein said core is loaded with said second compound in dissolved form.