ELDAR FINKELMAN HAGIT,LICHT MURAVA Avital,PLOTKIN BATYA
申请号：
IN1365/MUMNP/2013
公开号：
IN2013MN01365A
申请日:
2013.07.11
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
Novel peptide inhibitors of GSK 3 compositions containing same and uses thereof are disclosed. The novel peptide inhibitors are substrate competitive inhibitors and have an amino acid sequence designed so as to bind to a defined binding site subunit in GSK 3. Also disclosed are GSK 3 substrate competitive inhibitors which bind to the defined binding site subunit in the enzyme. Also disclosed are mutants of GSK 3 and uses thereof for identifying a putative GSK 3 substrate competitive inhibitor.
