THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;THE UNITED STATES OF AMERICA; AS REPRESENTED BY THE SECRETARY;ALETA BIOTHERAPEUTICS, INC.; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
LOBB, ROY,RENNERT, PAUL DAVID,SCHILLER, JOHN TODD
申请号：
CA3003728
公开号：
CA3003728A1
申请日:
2016.10.28
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Some embodiments of the present disclosure are directed to methods that include delivering to a subject a nucleic acid encoding an antigen, wherein the nucleic acid is delivered via a tumor-selective vehicle or via intratumoral injection, and delivering to the subject an immune cell expressing a receptor that binds to the antigen.
