FUSION PROTEINS COMPRISING MODIFIED ALLERGENS OF THE NS-LTPS FAMILY, USE THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME

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专利权人:

CONSIGLIO NAZIONALE DELLE RICERCHE

发明人:

GERACI, DOMENICO,BONURA, ANGELA,COLOMBO, PAOLO

申请号：

CA2558660

公开号：

CA2558660C

申请日:

2005.02.28

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

The present invention relates to fusion proteins comprising differentallergens of the ns-LTPs family, and their use in the prevention and thetreatment of allergic symptoms associated to said allergens. In particular,fusion proteins in the form of heterodimers comprising the major allergens ofParietaria judaica, Par 1 and Parj 2, are described. Methods of preparation ofthe fusion proteins by expression in genetically modified host cells andpharmaceutical compositions comprising said fusion proteins are described aswell.

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