COMPOSITIONS ET PROCÉDÉS D'INHIBITION DE L'ADHÉSION CELLULAIRE OU DU CIBLAGE D'AGENTS DIAGNOSTIQUES OU THÉRAPEUTIQUES VERS DES SITES DE LIAISON DE RGD

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专利权人:

Allegro Pharmaceuticals; LLC

发明人:

申请号：

EP19164968.0

公开号：

EP3586879A1

申请日:

2010.11.10

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

Compounds comprising R-G-Cysteic Acid (i.e., R-G-NH-CH(CH2- SO3H)COOH or Arg-Gly-NH-CH(CH2-SO3H)COOH) and derivatives thereof, including pharmaceutically acceptable salts, hydrates, stereoisomers, multimers, cyclic forms, linear forms, drug-conjugates, pro-drugs and their derivatives. Also disclosed are methods for making and using such compounds including methods for inhibiting cellular adhesion to RGD binding sites or delivering other diagnostic or therapeutic agents to RGD binding sites in human or animal subjects.

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