Disclosed is a compound having an inhibitory effect on both EGF receptor tyrosine kinase and HER2 tyrosine kinase. Specifically disclosed is a compound represented by the general formula (I) below, a pharmaceutically acceptable salt thereof or a solvate of either of them. [In the formula (I), R<；SUP>；1<；/SUP>； represents a C<；SUB>；1-3<；/SUB>； alkyl group or the like； R<；SUP>；2<；/SUP>； represents a group represented by the following formula: (wherein R<；SUP>；4<；/SUP>； and R<；SUP>；5<；/SUP>； independently represent a hydrogen atom, an optionally substituted alkyl group or the like； Ar<；SUP>；1<；/SUP>； represents an allylene or heteroallylene； R<；SUP>；6<；/SUP>； represents an optionally substituted alkyl group, an alkoxycarbonyl group or the like； R's independently represent an optionally substituted alkyl group, an alkyloxy group or the like； and n represents an integer of 0-2)； Y represents -O-, -S-, -N(R<；SUP>；20<；/SUP>；)- or the like； R<；SUP>；20<；/SUP>； represents a hydrogen atom, an alkyl group, an acyl group or the like； and R<；SUP>；3<；/SUP>； represents an optionally substituted phenyl group or the like.]
