NON HUMAN ANIMALS HAVING A HUMANIZED CLUSTER OF DIFFERENTIATION 47 GENE

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专利权人:

发明人:

GURER CAGAN,IOFFE ELLA,MUJICA ALEXANDER,THURSTON GAVIN

申请号：

IN201717019189

公开号：

IN201717019189A

申请日:

2017.05.31

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

Non human animals and methods and compositions for making and using the same are provided wherein said non human animals comprise a humanization of an endogenous cluster of differentiation (CD) gene in particular a humanization of a CD47 gene. Said non human animals may be described in some embodiments as having a genetic modification to an endogenous CD47 gene so that said non human animals express a CD47 polypeptide that includes a human portion and a non human portion (e.g. a murine portion).

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中国工程科技知识中心

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http://www.ckcest.cn/home/