A method of reducing an inflammation of a pulp or a periodontal ligament, said method comprising the steps of: (a) removing material from a pulp cavity and/or a root canal of a tooth； (b) rinsing pulp chamber with an anti-inflammatory rinse solution, (c) irrigating the root canal with an anti-inflammatory rinse solution to remove residual bacteria and/or smear layer, (d) providing an anti-inflammatory filling composition comprising: (i) at least 80% by weight of a premixed cement putty, said cement putty including at least one calcium silicate compound in the range of about 30% to about 90% by weight of said putty； and at least about 1% to about 50% of a liquid carrier including a water-soluble polymer and/or water-soluble oil； and (ii) about 3 to about 15% by weight of an anti-inflammatory agent, the anti-inflammatory agent including eugenol, vitamin E or mixtures thereof, and (e) introducing the anti-inflammatory filling composition into the cavity and/or root canal and allow the composition to harden.
