ANDREAS GOUTOPOULOS,BAYARD R. HUCK,CONSTANTIN NEAGU,JUSTIN POTNICK,LIZBETH CELESTE DESELM,MARK W. JR. CRONIN,ROCH BOIVIN,RUOXI LAN,THERESA L. JOHNSON,XIAOLING CHEN
申请号:
BR112015011974
公开号:
BR112015011974A2
申请日:
2013.11.27
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
Patent Summary: "Azaquinazoline carboxamide derivatives". The present invention relates to novel azaquinazoline carboxamide derivatives of formula (i) wherein w1, w2, w3, w4, r1, r2, r3 where defined above are inhibitors of p70s6k, and may be employed. , inter alia, for the treatment of hyperproliferative disorders.resumo patente de invenção: "derivados de azaquinazolina carboxamida". a presente invenção refere-se a novos derivados de azaquinazolina carboxamida de fórmula (i) (i) em que w1, w2, w3, w4, r1, r2, r3 e m que foram definidos acima, são inibidores de p70s6k, e podem ser empregados, inter alia, para o tratamento de distúrbios hiperproliferativos.