Bart De Strooper,Els Marjaux,Lujia Zhou,Serge Muyldermans
申请号:
US12736389
公开号:
US08568717B2
申请日:
2009.04.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Described are single domain antibodies with a specificity for BACE1. More specifically, described are single variable-domain antibodies derived from camelids that bind to BACE1 and are capable of inhibiting the activity of BACE1. The antibodies can be used for research and medical applications. Specific applications include the use of BACE1-specific antibodies for the treatment of Alzheimers disease.