A rice hybrid designated HR120001 (ATCC PTA-13290) is disclosed. The invention relates to the seeds of rice hybrid HR120001, to the plants of rice hybrid HR120001 and to methods for producing a rice plant produced by crossing the hybrid HR120001 with itself or another rice plant. The invention further relates to hybrid rice seeds and plants produced by crossing the hybrid HR120001 with another rice plant. This invention further relates to growing and producing blends of rice seeds comprised of seeds of rice hybrid HR120001 with rice seed of one, two, three, four, or more of another rice hybrid, rice variety or rice inbred.