Sodium having phenyl C- glucoside structures present invention, - glucose cotransporter 2 (SGLT2) inhibitors, their preparation, pharmaceutical compositions containing them and their use in the preparation of anti-diabetic drugs and the treatment of diabetes about. The present invention of the general formula I In the formula, the definition of R 5 and R 6, the following: (1) R5 = R6 = Me, (2) R5 = Me, R6 = OMe, (3) R5 = Me, R6 = H, (4) R5 = Me, R6 = F, (5) R5 = F, R6 = (6) R5 = OMe, R6 = H and H, Is selected from] [Formula 1] Provides compounds having the structure of the prodrug esters and salts and their pharmaceutically acceptable.本発明は、フェニルC-グルコシド構造を有するナトリウム-グルコース共輸送体2(SGLT2)阻害剤、その調製方法、それを含有する医薬組成物、並びに、糖尿病の治療及び抗糖尿病薬の調製におけるその使用に関する。本発明は、一般式I[式中、R5及びR6の定義は、以下:(1)R5=R6=Me、(2)R5=Me、R6=OMe、(3)R5=Me、R6=H、(4)R5=Me、R6=F、(5)R5=F、R6=H、及び(6)R5=OMe、R6=Hから選択される]【化1】の構造を有する化合物、並びにその薬学的に許容される塩及びプロドラッグエステルを提供する。
