TASTE-MASKED FORMULATIONS OF RALTEGRAVIR

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专利权人:

MERCK SHARP & DOHME CORP.

发明人:

THOMPSON, KAREN CASSIDY,KAIGHN, KIMBERLY NICOLE,MUKHERJEE, INDRA NEIL,DIIMMLER, CATHERINE ELIZABETH,WEISER, HEDY TEPPLIER,MANCINELLI, CHRISTOPHER

申请号：

CA2833006

公开号：

CA2833006A1

申请日:

2012.04.19

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

Disclosed are taste-masked pharmaceutical formulations of raltegravir comprising coated API granules mixed with a screened powder excipient blend in either tablet or sachet form. The core and coated granules are produced using a Wurster process for enhanced control of particle size. Also disclosed are methods of treating HIV, e.g., in pediatric populations.

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