A packaging material includes an antimicrobial agent adhered to a substrate. The antimicrobial agent can include copper, and the packaging material can include cellulose. The substrate can be paperboard, and the copper can be a copper salt, such as copper sulfate. The packaging material may be provided by causing adherence between the substrate and the antimicrobial agent, such as by coating the substrate with the antimicrobial agent. Then, the packaging material may be cut into sheets. The sheets may be formed into cartons or other suitable packages.