A biopsy device (10) may be used to obtain a tissue sample, such as a breast tissue biopsy sample. A biopsy device (10) may include an outer cannula (26) having a distal piercing tip (32), a cutter lumen, and a cutter tube (24) that rotates and translates past a side aperture (30) in the outer cannula (26) to sever a tissue sample. An exemplary sample capturing structure (34) (e.g., platter, barrel, etc.) has a plurality of sample cavities (e.g., radially symmetric, revolver handgun orientation, etc.) that are aligned one at a time (e.g., manually, etc.) to capture and store one or more tissue samples. A transmission mechanism may be operably configured to convert a trigger actuation motion into translation of the cuffer tube (24), hence enabling the biopsy device (10) to be operable by a single hand of a user to obtain a biopsy sample.
