ЛИ Чон-Ук (KR),ЛИ Сан-Хо (KR),ИМ Тхэк-Чу (KR),Го Ын-Чи (KR)
申请号:
RU2014125702
公开号:
RU2014125702A
申请日:
2012.11.28
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. A pharmaceutical composition for the prophylaxis or treatment of hyperlipidemia, comprising a compound of formula 1 or a pharmaceutically acceptable salt thereof and an angiotensin II receptor blocker as active ingredients 2. The pharmaceutical composition according to claim 1, wherein the angiotensin II receptor blocker is selected from the group consisting of olmesartan or its salt, medmesomil olmesartan or its salt, telmisartan or its salt, losartan or its salt and valsartan or its salt. The pharmaceutical composition of claim 1, wherein the angiotensin II receptor blocker is olmesartan medoxomil or a salt thereof. A pharmaceutical composition according to any one of claims 1 to 3, wherein the hyperlipidemia is hypertriglyceridemia or a hypertriglyceridemia-induced disease. The pharmaceutical composition of claim 4, wherein the hypertriglyceridemia-induced disease is atherosclerosis or pancreatitis. The pharmaceutical composition according to any one of paragraphs. 1-3, in which hyperlipidemia is hypercholesterolemia. 7. The pharmaceutical composition according to any one of paragraphs. 1-3, in which hyperlipidemia is a mixed hyperlipidemia. 8. The pharmaceutical composition according to any one of paragraphs. 1-3, in which the composition is prepared in a dosage form for oral administration. The pharmaceutical composition of claim 8, wherein the oral dosage form comprises a compound of formula 1 or a pharmaceutically acceptable salt thereof in an amount intended for administration in a dose in the range of 10 mg / day to 300 mg / day. The pharmaceutical composition of claim 8, wherein the finished drug1. Фармацевтическая композиция для профилактики или лечения гиперлипидемии, содержащая соединение формулы 1 или его фармацевтически приемлемую соль и блокатор рецепторов ангиотензина II в качестве активных ингредиентов2. Фармацевтическая композиция по п. 1, в которой блокатор рецепторов ангиотензина II выбирают из группы, состоящей из олмесартана или его соли, о