Byoung S. Kwon,Young Ho Kim,Mun Ki Kim,Kwang Hee Kim,You Hyun Kang,Sae Rom Lee
申请号：
US16715521
公开号：
US20200172866A1
申请日:
2019.12.16
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to a method of preparing cancer antigen-specific CD8+ T cells comprising (a) activating the CD8+ T cells from among PBMCs comprising cancer antigen-specific CD8+ T cells, and then expressing a co-stimulatory factor of these CD8+ T cells； (b) selecting the CD8+ T cells expressing a co-stimulatory factor among the cells activated in step (a)； (c) increasing the number of CD8+ T cells selected in step (b)； (d) freezing the CD8+ T cells obtained in step (c)； and (e) thawing the CD8+ T cells that were frozen in step (d).
