As defined with this bill, formula (i)The displacement indazole derivative and that salt which can be allowed pharmacy, those preparation manners and the medicine constituent which includes those are disclosed. The chemical compound of this invention loss of synchronism can become useful in medical therapy of remedy of the disease such as the cancer which it is related to the protein kinase activity which is moderate.本明細書で定義されている通りの式(I)の置換インダゾール誘導体および薬学的に許容できるその塩、それらの調製方法ならびにそれらを含む医薬組成物が開示される。本発明の化合物は、脱調節されたタンパク質キナーゼ活性に関連する癌などの疾患の治療の療法に有用となり得る。
