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COMPOSITION DE ZOLPIDEM ET SON PROCÉDÉ DE PRÉPARATION
专利权人:
Athena Drug Delivery Solutions Pvt Ltd.
发明人:
申请号:
EP16827382.9
公开号:
EP3324971A4
申请日:
2016.06.30
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Disclosed is a zolpidem composition and a process for preparing the same. The zolpidem composition comprises: zolpidem tartrate and polacrillin potassium in a weight ratio of 1:8. The process for preparation of a zolpidem composition comprises: mixing zolpidem tartrate and polacrillin potassium in a weight ratio of 1:8 to form a taste masked dry mix; mixing the pharmaburst B2, lactose monohydrate, colloidal silicon dioxide anhydrous, a sweetener, and a flavorant to form a flavor blend; blending of the taste masked dry mix and the flavor blend to form an intermediate blend; mixing of intermediate blend with magnesium stearate to form ready to compress granules of the zolpidem composition; and compressing the ready to compress granules of the zolpidem composition to form a sublingual oral disintegrating tablet.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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