Institute of Organic Chemistry and Biochemistry ASCR; v.v.i.
发明人:
BIRKUS, Gabriel,PAV, Ondrej,ROSENBERG, Ivan,SIMAK, Ondrej
申请号:
AU2019247904
公开号:
AU2019247904A1
申请日:
2019.04.04
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The present disclosure relates to 2'3'-cyclic dinucleotides modified with a 2'- or 3'-phosphonoalkyl bond and derivatives thereof, that can modulate the activity of the STING adaptor protein (IA) or a compound of Formula (1B) or pharmaceutically acceptable salt thereof wherein L