The University of Bath;Torrey Pines Institute for Molecular Studies;SRI International
发明人:
LEWIS, John,HUSBANDS, Stephen,TOLL, Lawrence
申请号：
ES14827852
公开号：
ES2784690T3
申请日:
2014.12.05
申请国别(地区):
ES
年份:
2020
代理人:
摘要：
The present invention relates to opioid compounds, especially to C14 esters and ethers of naltrexone and analogues thereof. The present invention also relates to compositions, methods and medical uses that employ such compounds. More specifically, the present invention pertains to compounds of formula: and to their use in the treatment of diseases and disorders including pain, hyperalgesia, addiction, substance abuse disorders, stress, anorexia, anxiety, depression, cough, asthma, hypertension, gastrointestinal motility disorder, water retention, cognitive disorders, and locomotor disorders.
