CRYSTAL FORM OF 3-ETHYL-4- {3-ISOPROPYL-4- (4- (1-METHYL-1H-PYRAZOL-4-YL) -1H-IMIDAZOL-1-YL) -1H-PYRAZOLO [3,4-B ] pyridin-1-yl} benzamide

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专利权人:

Taiho Pharmaceutical Co.; Ltd.

发明人:

UNO, Takao

申请号：

DK16792715

公开号：

DK3296299T3

申请日:

2016.05.11

申请国别(地区):

DK

年份:

2019

代理人:

摘要：

Provided are crystals of 3-ethyl-4-{3-isopropyl-4-(4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl}benzamid which are stable and show excellent oral absorbability. The crystals are Form II crystals of 3-ethyl-4-{3-isopropyl-4-(4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl}benzamide showing an X-ray powder diffraction spectrum having at least three characteristic diffraction peaks at angles (2¸ ± 0.2°) selected from the group consisting of 7.7°, 8.0°, 11.1°, 12.5°, 12.9°, 15.2°, 15.8°, 17.2°, 19.0°, 22.5°, 26.1°, and 27.4°.

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