LEBLOND BERTRAND,BEAUSOLELL ERIC,TAVERNE THIERRY,DONELLO JOHN E
申请号：
IN8326/DELNP/2015
公开号：
IN2015DN08326A
申请日:
2015.09.14
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
A compound of the formula: or a pharmaceutical!} acceptable sail thereof, wherein: Ri is IT or alkyl of I to 6 carbons R2 is selected from the gimip consisting of IIt and alkyl of 1 to 6 carbons or the Rj and R2 groups together with the nitrogen atom to which they arc shown at Inched form a saturated or unsaturated 4, 5, 6 or.7 member ed ring that optionally additionally includes one or two heteroatoms independently selected from the group consisting of N, O and S, said 4, 5, 6 ov7 membered ring optionally being substituted with one or two CO OH, CH2OII, Oil, B(OII)2, halogen groups, eyano groups or with one or two alkyl groups having ] to 6 carbons R3 is II, COR7 ov CO(>R7 where Ry is H, alkyl of 1 to 20 carbons, cyctoalkyl of 3 to 6 carbons, aryl or heteroaryl, aryl- alkyl, aryl(hydroxy)alkyl, heteroaryl-alkyl or hetcroalkyl(hydroxy)alkyl where the alkyl moiety hits I to 4 carbons, said aryl or hctcitiaiyl groups being optionally substituted with 1 to 3 groups independently selected from the group consisting of halogen, aikyl of 1 to 6 carbons, aLkoxy of 1 to 6 carbons and tin ox y of I to 3 carbons R� is II, alkyl of 1 lo 6 carbons, or CO RR where R� is alkyl of 1 to 6 carbons R5 and R arc independently selected 1mm the group consisting of H, halogen, alkyl of I to 6 carbons, aLkoxy of 1 to 6 carbons and thioxy ofl to 3 carbons or R5 and Rg together with the atoms lo which they are attached jointly fbiTn a carbocyclic or a heterocyclic ring, the carbocyclic ring having 5 or 6 atoms in the ring, the heterocyclic ring having 5 or 6 atoms in the ring and 1 to 3 hcteroatoms independently selected from N, O and s said carbocyclic or heterocyclic ring jointly formed by R5 and RG being optional \y substituted with I to 6 Ro groups where R<> is independently selected from halogen, alkyl. of 1 to 6 carbons, alkoxy of I to 6 carbons, and the wavy lines represent bonds of the alpha or beta configuration with the proviso that the formula excludes the compound o
