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Liquid agent for Topical Treatment of dermatophytosis
专利权人:
MEIJI SEIKA PHARMA CO.; LTD.
发明人:
YOSHIKO FURUTA,KAZUKI KOMATSU,ARPANSIREE KAYA,SHO TAKAHATA,YUJI TABATA
申请号:
ARP130102697
公开号:
AR092358A1
申请日:
2013.07.30
申请国别(地区):
AR
年份:
2015
代理人:
摘要:
In accordance with the present, a topical liquid agent having antifungal activity against dermatophytes and also high nail permeability can be provided. The topical liquid agent for nails and / or skin for the prevention or treatment of dermatophytosis comprises a film-forming agent and a compound represented by the formula (1) wherein R¹ represents a hydrogen atom, C₁₋₆ alkyl or trifluoromethyl, R² represents a hydrogen atom, C₁₋₆ alkyl,halogen, -COO (C₁₋₆ alkyl) or (CH₂) ₁₋₃COOR, where R represents a hydrogen atom or C₁₋₆ alkyl,R³ represents a hydrogen atom, C₁₋₆ alkyl,amino, trifluoromethyl or OR, where R represents a hydrogen atom or C₁₋₆ alkyl,R83088 represents a hydroxyl group, r83099 represents a hydrogen atom, i.e. c832131 tar;a hydroxyl or halogen group, R⁶ represents a hydrogen atom, C₁₋₆ alkyl,Keywords trifluoromethane, halogen, amino nr7491; r74955;nitro, hydroxy-C₁₋₆ alkyl,-CONRᵃRᵇ,-COO (alquilo C)-COOH, - (CH₂) ₁₋₃COOR or ORᵃ where R represents a hydrogen atom or C₁₋₆ alkyl,Rᵃ and Rᵇ may be the same or different from each other and each represents a hydrogen atom, C₁₋₆ alkyl or C₁₋₆ acyl,R⁷ represents a hydrogen atom, C₁₋₆ alkyl,-OR, where R represents a hydrogen atom or C₁₋₆ alkyl or halogen, R⁸ represents a hydrogen atom, C₁₋₆ alkyl,A hydroxyl, amino, or nitro group, or one of the salts.De acuerdo con la presente, se puede proporcionar un agente líquido tópico que tenga actividad antifúngica contra dermatofitos y también alta permeabilidad en uñas. El agente líquido tópico para las uñas y/o la piel para la prevención o el tratamiento de dermatofitosis comprende un agente formador de película y un compuesto representado por la fórmula (1) en donde R¹ representa un átomo de hidrógeno, alquilo C₁₋₆ o trifluorometilo, R² representa un átomo de hidrógeno, alquilo C₁₋₆, halógeno, -COO(alquilo C₁₋₆) o (CH₂)₁₋₃COOR, donde R representa un átomo de hidrógeno o alquilo C₁₋₆, R³ representa un átomo de hidrógeno, alquilo C₁₋₆, amino, trifluorometilo u OR, donde R
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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