Anilkumar R. Kore,Shanmugasundaram Muthian,Kyle Gee
申请号：
US15178821
公开号：
US09752153B2
申请日:
2016.06.10
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Alkynyl-derivatized cap analogs, alkynyl-modified capped RNA, 1,4-disubstituted triazole-derivatized capped RNA, methods of preparation, methods of isolation, and uses thereof are provided. The “click” modification facilitates detection and isolation of capped RNAs and the 1,4-disubstituted triazole derivatives formed by the “click” reaction are useful for producing RNA transcripts and encoded protein.
