A powder preparation for nasal administration containing a particulate of steroid hormones having an average particle size of 50 to 300 µm as an active ingredient is prepared. The powder preparation for nasal administration may further contain a water-soluble polymer (particularly, water-soluble polysaccharides such as a cellulose having a hydroxyalkyl group). The particulate of steroid hormones may be testosterone and/or a derivative thereof. The water-soluble polymer may be in a particulate form. The ratio of the water-soluble polymer may be about 1 to 50 parts by weight relative to 1 part by weight of the particulate of steroid hormones. The powder preparation for nasal administration may be a powder preparation for nasal administration which can control a Cmax of steroid hormones to not more than 15 ng/ml. A powder preparation for nasal administration which can control a plasma concentration of steroid hormones such as testosterone in a specific range for a long period of time is provided.
