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Antimicrobial preparation with retarded release of the biologically active component, utilization thereof and process for implant obtaining
专利权人:
HERAEUS KULZER GMBH
发明人:
SCHNABELRAUCH MATTHIAS,VOGT SEBASTIAN,KUEHN KLAUS-DIETER
申请号:
NO20021390
公开号:
NO331876B1
申请日:
2002.03.20
申请国别(地区):
NO
年份:
2012
代理人:
摘要:
The invention refers to antimicrobial preparations for implants, used in medicine and veterinary medicine for treatment of local microbial infections of the soft and solid tissues. The claimed antimicrobial preparation is a mixture consisting of at least one amphiphilic component, represented by sulphates, sulphamates or sulphonates, as well as of at least one antimicrobial component from the group of aminoglycosides, lincosamides, 4-quinolones or tetracyclines and, possibly, of at least one auxiliary anhydrous organic and/or inorganic component and of one biologically active component.The claimed preparation possesses a retarded release action of the biologically active component.Claims: 16Den foreliggende oppfinnelsen vedrører et antibiotikum-Zantibiotika-preparat for resorberbare og ikke-resorberbare implantater for human- og veterinærmedisin, for behandling av lokale mikrobielle infeksjoner i hard- og i mykvev. Antibiotikum-Zantibiotika- preparatet ifølge oppfinnelsen er en blanding bestående av minst en amfifil komponent av en representant for alkylsulfatene, alkylarylsulfatene, cykloalkyisulfatene, alkylcykloalkylsulfatene, alkylsulfamatene, cykloalkylsulfamatene, alkylcykloalkylsulfamatene, arylsulfamatene, alkylarylsulfamatene, alkylsulfonatene, fettsyre-2-sulfonatene, arylsulfonatene, alkylarylsulfonatene, cykloalkylsulfonatene, alkylcykloalkylsulfonatene, alkyldisulfatene, cykloalkyldisulfatene, alkyldisulfonatene, cykloalkyldisulfonatene, aryldisulfonatene, alkylaryldisulfonatene, aryltrisulfonatene og alkylaryltrisulfonatene såvel som minst en antibiotisk komponent fra gruppen av aminoglykosid- antibiotika, linkosamid-antibiotika. 4-kinolon-antibiotika eller tetracyklin-antibiotika og eventuelt minst en vannfri, organisk hjelpekomponent og eventuelt minst en uorganisk hjelpekomponent og eventuelt minst en biologisk aktiv hjelpekomponent. Antibiotikum-Zantibioitika-preparater ifølge oppfinnelsen utviser en retarderende virkestoffrigivnig.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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