Nicolas LHeureux,Todd N. McAllister,Nathalie Dusserre
申请号:
US14387323
公开号:
US20150088247A1
申请日:
2013.03.25
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A single-layer tissue sheet having a puncture strength of 2 kgf to 6 kgf. A valve, such as a heart valve, made of one or more leaflets formed from a single-layer tissue sheet. A method of making a tissue sheet having a puncture strength of 2 kgf to 5 kgf. The ultra-strong tissue sheets described herein have very long culture times, such as in excess of 20 weeks. Valves that comprise one or more leaflets made from the ultra-strong tissue sheets described herein may be delivered via trans-cathete aortic valve implantation.