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COMPOSITIONS AND METHODS FOR THE TREATMENT OF SEXUAL DYSFUNCTION
专利权人:
Vijaykumar Rajasekhar
发明人:
Vijaykumar Rajasekhar
申请号:
US15173398
公开号:
US20160354444A1
申请日:
2016.06.03
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Described herein are pharmaceutical compositions for the treatment of sexual dysfunction in an individual. In some embodiments, the pharmaceutical composition includes a prolactin variant having a glycine residue at position 129 substituted with an amino acid other than glycine. In one embodiment, the amino acid is arginine. In one embodiment, the prolactin variant further comprises an N-terminal deletion. In one embodiment, the prolactin variant is conjugated to a H(OCH2CH2)nOH molecule (e.g., n equals any number from 1 to 6). In some embodiments, the pharmaceutical composition is delivered to the individual by a microneedle patch or an inhalable formulation.
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