Kishnani, Kunal;Ramaswamy, Shankar;Friedhoff, Lawrence Tim;Lewis, Bryan M;Axovant Sciences GmbH;Piscitelli, Stephen Clement
发明人:
Friedhoff, Lawrence Tim,Kishnani, Kunal,Lewis, Bryan M,Piscitelli, Stephen Clement,Ramaswamy, Shankar
申请号:
NO20171941
公开号:
NO20171941A1
申请日:
2017.12.05
申请国别(地区):
NO
年份:
2017
代理人:
摘要:
The present application relates to new uses of 5-HT6 receptor antagonists, specifically 3-phenylsulfonyl-8-piperazinyl-1yl-quinoline or pharmaceutically acceptable salts, hydrates, solvates, or polymorphs, thereof, and to the combination of 5-HT6 receptor antagonists, specifically 3-phenylsulfonyl-8-piperazinyl-1yl-quinoline or pharmaceutically acceptable salts, hydrates, solvates, or polymorphs, thereof, with other therapeutic agents for the treatment of a neurodegenerative disease.The present application relates to new usesof5-HT6 receptorantagonists, specifically high doses of 3- phenylsulfonyl-8-piperazinyl-lyl-quinoline, and to the combination of 5-HT6 receptorantagonists,specifically 3-phenylsulfonyl-8-piperazinyl-lyl-quinoline, with, an acetylcholinesterase inhibitorforthe treatment of a neurodegenerative disease.