HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF

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专利权人:

CHDI FOUNDATION; INC.

发明人:

DOMINGUEZ, Celia,HUGHES, Samantha, J.,JARVIS, Rebecca, E.,VATER, Huw, D.,PENROSE, Stephen, D.,WALL, Michael,STOTT, Andrew, J.,SAVILLE-STONES, Elizabeth,MUÑOZ-SANJUAN, Ignacio,LUCKHURST, Christopher,

申请号：

USUS2015/033511

公开号：

WO2015/187542A8

申请日:

2015.06.01

申请国别(地区):

WO

年份:

2016

代理人:

摘要：

Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use. The condition or disorder mediated by HDAC comprises a neurodegenerative pathology. Accordingly, also provided is a method of treating a neurodegenerative pathology mediated by HDAC in a subject in need of such a treatment, comprising administering to the subject a therapeutically effective amount of at least one compound, or pharmaceutically acceptable salt thereof, described herein.Linvention concerne certains inhibiteurs dhistone désacétylase (HDAC) de formule I, des compositions de ceux-ci, et des méthodes dutilisation de ceux-ci.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/