Benjamin T. Reves,Roger E. Harrington,Jerbrena C. Jacobs,David S. Scher,Daniel A. Shimko
申请号：
US15620189
公开号：
US20180353654A1
申请日:
2017.06.12
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided is an implant configured to fit at or near a bone defect to promote bone growth. The implant comprises an oxysterol uniformly disposed in an acellular tissue matrix (ATM). The acellular tissue matrix can be porcine collagen, which in some cases is crosslinked. The implant can contain an acellular porcine crosslinked collagen in an amount of about 5 wt. % to about 25 wt. % of the implant and an oxysterol in an amount of about 5 wt. % to about 90 wt. % of the implant. The oxysterol can be Oxy133 monohydrate or an Oxy133 polymorph. Methods of making and using the implant are further provided.
