Keith S. Learn;Bruce Dorsey;Daming Feng;Henry Joseph Breslin;Diane E. Gingrich;Jason Burke;Joseph G. Lisko;Eugen;Benjamin J. Dugan;Rong-Qiang Liu;Matthew A. Curry;James L. Diebold;Tao Guo;Gulzar Ahmed
发明人:
Gulzar Ahmed,Henry Joseph Breslin,Jason Burke,Matthew A. Curry,James L. Diebold,Bruce Dorsey,Benjamin J. Dugan,Daming Feng,Diane E. Gingrich,Tao Guo,Keith S. Learn,Joseph G. Lisko,Rong-Qiang Liu,Eugen
申请号:
US12162851
公开号:
US08148391B2
申请日:
2007.10.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides a compound of formula I or II or a pharmaceutically acceptable salt form thereof, wherein R1, R2, R3, R4, R5, A1, A2, A3, A4, and A5, are as defined herein. The compounds of formula I or II have ALK and/or c-Met inhibitory activity, and may be used to treat proliferative disorders.