FIELD: chemistry.SUBSTANCE: invention relates to substituted 2-oxy-quinoline-3-carboxamides of general formula (I) in form of free compounds or salts of physiologically acceptable acids or bases, where R1 is C1-6-aliphatic residue； 6-member unsubstituted or mono- or disubstituted aryl or unsubstituted 5-member heteroaryl, selected from a thienyl； R2 is CF3； C1-4-aliphatic residue； O-C1-4-aliphatic residue； R3, R4, R5 and R6 each independently represent H； F； Cl； Br； I； CN； CF3； R7 is C1-6-aliphatic residue, unsubstituted or mono- or trisubstituted； where "aliphatic residue" in each case may be branched or straight, saturated, where "mono- or trisubstituted" with respect to "aliphatic residue" relates, in relation to corresponding residues, to substitution of one or three hydrogen atoms, each independently from other, with at least one substitute selected from a group which includes F, Cl, Br, I, OH, O-C1-4-aliphatic residue, where "mono- or disubstituted" with respect to "aryl" relates, in relation to corresponding residues, to substitution of one or two hydrogen atoms, each independently from other, with at least one substitute selected from a group which includes F, Cl, Br, I, OH, O-C1-4-aliphatic residue C1-4-aliphatic residue. Invention also relates to a pharmaceutical composition based on compound of formula (I) and a method of treating and/or preventing diseases mediated by channels KCNQ2/3 K+.EFFECT: obtaining novel 2-oxy-quinoline-3-carboxamide derivatives having useful biological activity.8 cl, 2 tbl, 53 exИзобретение относится к области органической химии, а именно к замещенным 2-окси-хинолин-3-карбоксамидам общей формулы (I) в виде свободных соединений или в виде солей физиологически приемлемых кислот или оснований, где R1 представляет собой C1-6-алифатический остаток； 6-членный незамещенный или моно- или дизамещенный арил или незамещенный 5-членный гетероарил, выбранный из тиенила； R2 представляет собой CF3； C1-4-алифатический остаток； O-C1-4-алифатическ
