It refers to a pharmacological synthesis, including: (a) phosphoric acid isomerization inhibitor-3 quinasa pi3kb, such as 2 - {2 - [(2S) - 2-methyl-2, 3-dihydro-1h-indol-1-il] - 2-oxoetil} - 6 - (morfolin-4-il) pirimidin-4 (3H) - ona; and (b) MEK quinasa or RA quinasa inhibitors on mapyk fengueb Avenue, such as muravi. This composition is very useful in cancer treatmentSE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: A) UN INHIBIDOR DE LA ISOFORMA DE LA FOSFOINOSITIDA-3 QUINASA PI3KB TAL COMO 2-{2-[(2S)-2-METIL-2,3-DIHIDRO-1H-INDOL-1-IL]-2-OXOETIL}-6-(MORFOLIN-4-IL)PIRIMIDIN-4(3H)-ONA; Y B) UN INHIBIDOR DE LA MEK QUINASA O RAF QUINASA DE LA VIA DE MAPK TAL COMO SELUMETINIB O VEMURAFENIB. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE CANCER