The present invention provides a kind of with HSP90 inhibiting effect and with the novel indazole compound of cancer cell multiplication inhibitory effect. In addition another project of the invention provides a kind of in the relevant diseases of the HSP90, particularly useful pharmaceuticals in the prevention and/or treatment of cancer in what base what HSP90 inhibiting effect. The following general formula (I) compound represented or its salt, the record in formula, in X, Y1~Y4, A, B, R1~R8 such as the claim of this application.本發明提供一種具有HSP90抑制作用、且具有癌細胞增殖抑制效果的新型吲唑化合物。另外本發明的另一個課題在於基於HSP90抑制作用，提供一種在該HSP90相關的疾病、特別是在癌症的預防和／或治療中有用的醫藥品。下述通式（Ⅰ）所示的化合物或其鹽，式中，X、Y1～Y4、A、B、R1～R8如本申請權利要求中的記載。
