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Stabilization of radiopharmaceuticals
专利权人:
GE Healthcare BV
发明人:
VAN DEN BOS, Jan
申请号:
AU2013204461
公开号:
AU2013204461A1
申请日:
2013.04.12
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
#$%^&*AU2013204461A120130509.pdf#####H:\rbrnItewvoven\NRPottbI\DCC\RBR\5070598_ .DOC.12/04/2013 ABSTRACT The invention relates to stabilised radiopharmaceutical compositions which 5 comprise: (i) an 18F-labelled compound (ii) an effective stabilizing amount of gentisic acid or a salt thereof with a biocompatible cation (iii) an aqueous biocompatible carrier medium 10 wherein the radioactive concentration of the 18F in the carrier medium is in the range 10 to 100,000 MBq/ml and the pH of the composition is in the range 4.0 to 9.5. The invention further comprises methods for preparing such radiopharmaceutical compositions and a new use of gentisic acid or a salt thereof. 15
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