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Biocompatible oligomer-polymer compositions
专利权人:
Richard L. Norton
发明人:
Richard L. Norton
申请号:
US12995910
公开号:
US09308162B2
申请日:
2009.06.03
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to biocompatible oligomer-polymer compositions for the in situ formation of implants, wherein the implants release a bioactive agent, a metabolite, or a prodrug thereof, at a controlled rate. The sustained release delivery system includes a flowable composition containing a bioactive agent, a metabolite, or a prodrug thereof, and an implant containing a bioactive agent, a metabolite, or a prodrug thereof. The flowable composition may be injected into tissue whereupon it coagulates to become the solid or gel, monolithic implant. The flowable composition includes a biodegradable, thermoplastic polymer, a biocompatible end-capped oligomeric liquid, and a bioactive agent, a metabolite, or a prodrug thereof.
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