Use of a RAR antagonist or inverse agonist for the treatment of chemotherapy and/or radiation therapy side effects

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专利权人:

Yang-Dar Yuan;Roshantha A. Chandraratna

发明人:

Roshantha A. Chandraratna,Yang-Dar Yuan

申请号：

US12291994

公开号：

US09271946B2

申请日:

2008.11.13

申请国别(地区):

US

年份:

2016

代理人:

摘要：

A method for treating chemo therapy or radiation therapy side effects in a mammal undergoing chemotherapy and/or radiation therapy, the method comprising a step of administering to the mammal a therapeutically effective amount of a RAR antagonist or RAR inverse agonist which binds to receptors of the RARα, RARβ and RARγ subtypes is disclosed. Such side effects include chemoradiotherapy-induced alopecia, chemoradiotherapy-induced thrombocytopenia, chemoradiotherapy-induced leucopenia and chemoradiotherapy-induced neutropenia.

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中国工程科技知识中心

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