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COMPOSITIONS AND METHODS FOR INDUCING SATIETY AND TREATING NON-INSULIN DEPENDENT DIABETES MELLITUS, PRE-DIABETIC SYMPTOMS, INSULIN RESISTANCE AND RELATED DISEASE STATES AND CONDITIONS
专利权人:
Volant Holdings GmbH
发明人:
Joseph M. Fayad
申请号:
US15623734
公开号:
US20180369177A1
申请日:
2017.06.15
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention provides methods of treatment that induce satiety in a subject for a period of at least around twenty-four hours by once-daily administration to the subject of a controlled release dosage form, wherein the dosage form is administered while the subject is in the fasted state and at a time of around six to around nine hours prior to the subject's next intended meal, and wherein the dosage form comprises a controlled release composition, which comprises an enterically-coated, ileum hormone-stimulating amount of a nutritional substance and releases the majority of the nutritional substance in vivo upon reaching the subject's ileum. The invention also provides a diagnostic tool for probing the health and disease state of the ileal hormones, excess or deficiencies. The invention provides a safe vehicle for targeted deliveries of chemical, pharmaceuticals, natural substances and nutrition to the ileum. The present invention also provides a method for treating noninsulin dependent diabetes mellitus, pre-diabetic symptoms, and insulin resistance, as well as a number of disease states and conditions including gastrointestinal disorders as otherwise described herein.
来源网站:
中国工程科技知识中心
来源网址:
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