Gerald J. Wallweber,John W. Winslow,Lisa DeFazio Eli
申请号：
US14781468
公开号：
US20160041171A1
申请日:
2014.04.07
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Systems and methods are provided for facilitating diagnosis, prognosis and treatment of cancer based on detection of HER3 activation. The systems and methods involve analysis of samples for the presence or the absence of activated HER3 markers as indicated by HER2-HER3 heterodimers, HER3 phosphorylation, or recruitment of PI3K to activated HER3 (HER3/PI3K complexes). The amounts of activated HER3 marker expression may be measured alone or in conjunction with other biomarkers.
