Michel Sadelain,Judith Feucht,Mohamad Hamieh,Jie Sun,Jorge A. Mansilla-Soto
申请号：
US16911148
公开号：
US20200317777A1
申请日:
2020.06.24
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The presently disclosed subject matter provides methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to novel designs of chimeric antigen receptors (CARs) and engineered immunoresponsive cells comprising the same. The engineered immunoresponsive cells comprising the novel CARs are antigen-directed and have extended persistence without compromising function.
