Marjan Huizing;Christopher M. Jay;Tal Yardeni;William A. Gahl;Nancy Smyth Templeton
发明人:
Marjan Huizing,Tal Yardeni,Christopher M. Jay,Nancy Smyth Templeton,William A. Gahl
申请号:
US13605946
公开号:
US20130058998A1
申请日:
2012.09.06
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A method for treating a disorder characterized by hyposialylation in a subject that includes administering to the subject an effective amount of (i) a composition comprising N-acetylmannosamine, or a derivative thereof, encapsulated within a liposome, or (ii) a composition comprising N-acetylneuraminic acid, or a derivative thereof, encapsulated within a liposome, wherein the liposome comprises 1,2-dioleoyl-3-trimethylammonium-propane and cholesterol.