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Process for the production of amides
专利权人:
SYNGENTA PARTICIPATIONS AG
发明人:
TOBLER, HANS,WALTER, HARALD,EHRENFREUND, JOSEF,CORSI, CAMILLA,GIORDANO, FANNY,ZELLER, MARTIN,SEIFERT, GOTTFRIED,SHAH, SHAILESH,GEORGE, NEIL,JONES, IAN,BONNETT, PAUL
申请号:
TW101130220
公开号:
TW201247628A
申请日:
2006.09.14
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
The present invention relates to a process for the preparation of compounds of formula I wherein R1 and R2 are each independently of the other hydrogen or C1-C5alkyl and R3 is CF3 or CF2H, by (a) reaction of a compound of formula II wherein R1 and R2 are as defined for formula I, with at least one reducing agent to form a compound of formula III wherein R1 and R2 are as defined for formula I, and (b) reaction of that compound with at least one reducing agent to form a compound of formula IV wherein R1 and R2 are as defined for formula I, and (c) reaction of that compound with a compound of formula V wherein Q is chlorine, fluorine, bromine, iodine, hydroxy or C1-C6alkoxy and R3 is as defined for formula I, to form the compound of formula I and to novel intermediates for use in that process.
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